Analysis of the Current Global Research Status and Hotspots of Vitiligo Pathogenesis Based on Bibliometrics

LI Jiang; KONG Jun

doi:10.11786/sypfbxzz.1674-1293.20250601

Abstract：Objective This study aims to analyze the current research status and development trends of the vitiligo pathogenesis,thus providing reference for future basic research and clinical treatment related to vitiligo.Methods We searched the Web of Science Core Collection(WOSCC)database for literature related to the vitiligo pathogenesis,covering the time period from January 1,2003 to December 31,2023.The CiteSpace,VOSviewer,and the bibliometrix package in R were employed,The research trends,authors,countries,research institutions,journals,keyword co-occurrence,keywords with citation bursts,and other results were included Bibliometrics and visual analysis.Results A total of 902 papers related to vitiligo pathogenesis were included in the analysis.The top three authors in rankings of the number of publications are Li Chunying Begum Rasheedunnsa,Gao Tianwen.Harris John E,ranked among the top 3 co cited authors Begum Rasheedunnsa,Dwivedi Mitesh.The top three publishing institutions are Egyptian Knowledge Bank(EKB),Cairo University,Air Force Medical University.The top three countries in the rankings are China,the United States,and India.The top three journals that have published papers related to vitiligo pathogenesis are Archives of Dermatological Research,Journal of Investigative Dermatology and Pigment Cell&Melanoma Research.The Journal of Investigative Dermatology has the highest number of citations.The paper"Vitiligo:Mechanisms of Pathogenesis and Treatment"has the highest citation intensity.The top three keywords with citation bursts are"human melanocytes","generalized vitiligo"and"autoimmune disease".The keywords with high citation intensity in the past 5 years include"unfolded protein response","expression","upregulation","proliferation","serum","peripheral blood","stress",and"interferon gamma".Conclusion The research on the pathogenesis of vitiligo by different countries,institutions,and authors has significant regional significance.In the past five years,research hotspots include unfolded protein response,interferon gamma,stress,etc.