Skin Leiomyoma in the Manifestation of Flat Xanthoma:a Case Report
WANG Ying
HUANG Qiong
Abstract：A 67-year-old female patient presented with a growingly enlarged pale yellow plaque for 2 years.A plaque of 2 cm× 1.5 cm in size could be seen on the patient's right buttock,showing an irregular morphology,light yellow in color,blurred margin,hard texture in touch,and drivable base.She occasionally experienced itching in the plaque,without pain and sting sensation.Histopathological examination revealed mild hyperkeratosis of the epidermis,proliferation of spindle shaped cells in the dermis,spindle-shaped muscle cells,long and blunt nucleus without nuclear atypia,and eosinophilic cytoplasm.Immunohistochemistry showed positivity for smooth muscle actin(SMA)and smooth muscle desmin(Des).The patient was diagnosed with skin leilmyoma and treated with surgical procedures.No recurrence was observed during the 18 months of follow-up.
Keywords：LeiomyomacutaneousXanthomaflat
Publication Date：2025-10-10
Online Publishing Date：2025-11-05(First online date of this platform, not the publication date of the document)
Pages：3( 395-397 )