A case of basaloid follicular hamartoma on the back with literature review
HU Xiangxiang
WANG Chaofu
LI Chuanying
Abstract：A case of basophilic follicular hamartoma is reported.A 41-year-old female patient presented with a painless subcutaneous mass on her back for half a year.Dermatological examination revealed a subcutaneous nodule about the size of a peanut,with a hard texture,protruding from the skin surface,clear boundaries,smooth surface,and no ulceration or exudation.Histopathological examination reveals that under light microscopy,the tumor is located in the dermis,presenting a lobulated pattern.The tumor cells are arranged in cord-like structures,with some connections between them.These cord-like structures are surrounded by basal cells,and the interstitium shows fibrous tissue hyperplasia.The cells exhibit no atypia,and no mitotic figures are observed.Immunohistochemical staining showed Bcl-2(weakly positive in a few cells),BerEP4(negative),low Ki67 index,and CD34(positive)in the stroma.Diagnosis:Basaloid follicular hamartoma.Complete excision was performed,and no recurrence was observed during 2 years of follow-up.
Keywords：Follicular hamartomabasaloid
Publication Date：2025-08-10
Online Publishing Date：2025-09-01(First online date of this platform, not the publication date of the document)
Pages：4( 314-317 )