Relationship between Mohs surgery excision depth and prognosis in 507 cases of nasal basal cell carcinoma
LV Jin
WAN Yuanyuan
WAN Xuefeng
Abstract：Objective To investigate the impact of Mohs surgery excision depth on the therapeutic effect of nasal basal cell carcinoma(BCC)and provide a basis for optimizing surgical protocols.Methods A total of 507 patients with pathologically confirmed primary nasal BCC treated at the Department of Dermatology,The First Affiliated Hospital of Xinjiang Medical University,from December 2017 to January 2022,were enrolled.Patients were grouped according to tumor anatomical regions,and Mohs surgery was performed with excision depths adjusted to anatomical layers:periosteum in the nasion-nasal bone region,nasal cartilage in the upper lateral nasal cartilage region,and nasal mucosa in the alar cartilage region.Age,lesion location,gender distribution,complete resection rate,and recurrence rate were statistically analyzed.Results Among 507 patients,58.8%(298 cases)were over 60 years old,and the alar cartilage region(37.1%,188 cases)was the most common site.The primary resection rates were 97.6%in the nasion-nasal bone region,96.8%in the upper lateral nasal cartilage region,and 95.7%in the alar cartilage region.No recurrences were reported during follow-up.Conclusion Adjusting Mohs surgery excision depth according to tumor anatomical regions improves surgical outcomes for nasal BCC.
Keywords：Nasal basal cell carcinomaMohs surgery
Publication Date：2025-08-10
Online Publishing Date：2025-09-01(First online date of this platform, not the publication date of the document)
Pages：4( 270-273 )