Research progress on scalp seborrheic dermatitis and scalp microbiome
LI Man
REN Wei
ZHANG Fan
Abstract：The pathogenesis of scalp seborrheic dermatitis remains unclear,and alterations in the scalp microbiome are likely to play a crucial role.Numerous studies have indicated that,compared with healthy individuals,patients with seborrheic dermatitis exhibit changes in the α-diversity of skin fungi,with no significant alterations in β-diversity.Specifically,there is an increase in the genus Malassezia restricta(M.restricta)and a decrease in Malassezia globosa(M.globosa).Both the α-diversity and β-diversity of bacteria are altered,mainly characterized by an increase in the genus Staphylococcus and a decrease in the genus Propionibacterium.Alterations in the diversity of scalp microecological metabolic functions play a significant role in the development of scalp seborrheic dermatitis.Moreover,they are associated with the severity of scalp seborrheic dermatitis and the function of the skin barrier.Research on the scalp microbiome may offer new perspectives for the treatment of scalp seborrheic dermatitis.
Keywords：DermatitisseborrheicScalp microbiomemicrobial population diversityResearch progress
Publication Date：2025-02-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 44-47 )