A case of schwannoma
JIA Hongxia
RAN Liwei
Abstract：A 45-year-old female with a nodule on her left thigh for 6 years.Dermatological condition:there was an ovoid dark purple subcutaneous nodule about 2 cm×3 cm in size on the left thigh which was slightly hard texture with a clear boundary and without obvious tenderness.Histopathology showed the tumor was located in the deep dermis and subcutaneous,ovoid and encapsulated,with typical Antoni A and Antoni B areas.Antoni A area was composed of dense spindle cells with tapering,enlongated,rather wavy nuclei;there was prominent nuclear palisading producing the distinctive Verocay bodies.In Antoni B area,scattered and spindled or stellate cells were set in an abundant loose myxoid stroma,and the hyalinezed walls of the small blood vessels were visible.Immunohistochemistry results showed that S-100 and SOX 10 were diffuse positive in the spindled cells,and EMA was positive in the peripheral capsule cells and Acinlan staining was positive.Diagnosis:schwannoma.The lesion was surgically excised.There was no recurrence after 3 months of follow-up.
Keywords：Schwannoma
Publication Date：2024-04-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 126-128 )