A case of porokeratosis with scaly plaques on the buttocks as the main manifestation
YU Shan-shan
ZHANG Wei
GU Heng
Abstract：A 52-year-old male patient with a rash on both forearms for 3 years,involving both buttocks and lower limbs for 2 months.Physical examination showed that large brown soybean-sized rashes with levee-like ridges scattered on both forearms and waist.On both buttocks,there were brownish hyperkeratotic verrucous plaques with well-demarcated satellite papules,partially fused into thin plaques with a rough surface and small scales.The edges were raised with a clear boundary.Rashes on both lower limbs were similar to those on the buttocks,and the eruptions,with no involvement of the genital region,were predominantly located on the flexural surfaces.The histopathology of the rash showed basketweave hyperkeratosis,columnar parakeratosis of the stratum corneum,multiple coronoid lamellae,and disappearance of the granular layer underneath.There was partial acanthosis and mild spongiosis.Few lymphocytes,eosinophils,and melanophages were present around the superficial dermal vessels.A diagnosis of porokeratosis was made.The patient was recommended oral acitretin capsules but discontinued oral medication after 1 month due to adverse reactions.The follow-up is ongoing,and the lesions did not improve significantly
Keywords：PorokeratosisgenitoglutealDifferential diagnosisTreatment
Publication Date：2023-12-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 383-384 )