Porphyria cutanea tarda:a case report
JI Cai-heng
WANG Jia-jia
WANG Ming-fa
Abstract：A 47-year-old male patient presented with erythema,papules,and blisters on his face,neck,back,and both upper extremities,accompanied by itchiness for more than 5 months.The lesions were aggravated by sun exposure and alcohol consumption.Liver function tests showed elevated transaminases,and the urine exhibited coral-red fluorescence under Wood's lamp.Whole-genome exome sequencing revealed no gene mutations.Histopathology of skin lesions revealed subepidermal blisters(without inflammatory cell infiltration),mucin deposition,and proliferation of collagen fibers in the subdermal layer.No fluorescent material deposition was observed by immunofluorescence.A final diagnosis of porphyria cutanea tarda was made.The symptoms were relieved after treatment with hydroxychloroquine and compound glycyrrhizin.No recurrence was observed during the 6-month follow-up.
Keywords：Porphyria cutanea tarda
Publication Date：2023-08-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 248-250 )