Pathological and dermoscopy features analysis of juvenile xanthogranuloma in 20 cases
DANG Yun
XIANG Gui-qiong
WANG Dan-dan
Abstract：Objective To explore the value of dermoscopy in the diagnosis of juvenile xanthogranuloma.Methods It was a retrospective study which analyzed the clinical,dermoscopic and pathological data of 20 cases with juvenile xanthogranuloma from July 2018 to March 2021 in our department.Results There were 12 males and 8 females.The average age at onset was 2.12±4.29 years old.Typical lesions are yellow,red or brown papules with a diameter of several millimetres to several centimetres in size,which have the hard and smooth surface.The skin lesions of 20 patients were single.Histopathologic examination showed well-circumscribed mass composed of foamy histiocytes inflammatory cells and Touton giant cells in the dermis.Among 20 patients the dermoscopic patterns of juvenile xanthogranuloma were yellow-orange and/or pink-red structureless color with vascular structures.The setting sun appearance were present in seventeen patients(85%),The clouds of paler yellow globules were present in thirteen patients(65%)whitish streak were present in five patients(25%).Vascular structures were observed in an irregular distribution,with linear vessels(60%),dotted vessels(55%),and branched vessels(35%).Conclusion Juvenile xanthogranuloma has characteristic dermatoscopic patterns which can be used as an auxiliary diagnostic technique of juvenile xanthogranuloma.
Keywords：XanthogranulomajuvenileClinical featuresPathological featuresDermoscopy
Publication Date：2023-08-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 202-205 )