Clinical observation on directional drug permeation of xiaoban application in the treatment of plaque psoriasis
Abstract：Objective To observe the clinical effect of directional drug permeation of xiaoban application in the treatment of plaque psoriasis. Methods By using random number table method, a total of 60 patients with plaque psoriasis were divided into treatment group and control group, with 30 cases in each group. The treatment group was treated with oral administration of Chinese herbal medicine Huoxue Sanyu Decoction, and the Xiaoban application was introduced into the skin lesions 3 times a week by using the Chinese herbal medicine permeameter. The control group was treated with oral administration of Chinese herbal medicine Huoxue Sanyu Decoction and white vaseline externally once a day. The therapeutic efficacy was evaluated before and 4 weeks after the treatment by PASI score, TCM syndrome score, itching index score and dermatology life quality index(DLQI). Results The total effective rate was 89.65% in the treatment group and 65.51% in the control group respectively, and there was significant difference between the two groups in total effective rate(P<0.05). After treatment, the PASI score, itching index scores and DLQI of the treatment group were significant lower than those of the control group, and the difference had statistical significance(P<0.05). There was no significant difference in the TCM syndrome scores between the two groups(P>0.05). Conclusion Directional permeation of xiaoban application has positive curative effect in the treatment of plaque psoriasis.
Keywords：Psoriasisxiaoban applicationDirectional drug permeation
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 289-291 )