The curative effect evaluation of photodynamic therapy with three different photosensitizer carriers for condyloma acuminatum
YIN Tao
Abstract：Objective To observe the efficacy and safety of 5-aminolevulinic acid photodynamic therapy(ALA-PDT) with three kinds of photosensitizer carriers for condyloma acuminatum(CA).Methods One hundred and twenty CA patients were divided equally into three groups randomly:the sterilized water group,the ground substance cream group and the temperature-sensitive gel group.Three groups were treated respectively by ALA-PDT with the photosensitizer carrier of the sterilized water,the ground substance cream and the temperature-sensitive gel.The patients were treated three times for every 7-10 days.The clinical efficacy was analyzed four months later after the treatment.Results The complete remission rate of the three groups was 75.7％,78.4％ and 89.5％ respectively.The relapse rate was 35.7％,31.0％ and 17.6％ respectively.The significant difference of the complete remission rate and the relapse rate between the temperature-sensitive gel group and the other two groups existed.Conclusion The efficacy of photodynamic therapy in the treatment of CA with the photosensitizer carrier of the temperature-sensitive gel precedes the PDT with the sterilized water or the ground substance.
Keywords：Condyloma acuminatumPhotodynamic therapyDosage form
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 82-84 )