Local injection of 2% lidocaine combined with oral gabapentin in the treatment of post-herpetic neuralgia
WANG Fei-fei
WANG Rui
DUAN Jiao-xiong
Abstract：Objective To study the effect and safety of local injection of 2% lidocaine combined with gabapentin in the treatment of post-herpetic neuralgia(PHN). Methods A total of 100 patients with PHN were randomly divided into two groups: Gabapentin group ( group A, n=50) and local injection of 2% lidocaine combined with gabapentin group ( group B, n=50). The effects were valuated by visual analogue scale (VAS) and according to 24-hour sleeping time, and the side effects and complications were also observed. Results The pain scores after the treatment decreased with time compared with those before treatment in 2 groups during 10 days, both the decrease of VAS and the sleeping time within 24 hours were higher in group B (P<0.05). Compared with group A, sleeping time in 24 hours increased more in group B (P<0.05). Side effects and complications were not found in the two groups. Conclusion The strategy of local injection of 2% lidocaine combined with gabapentin is effective and safe for the treatment of PHN, which is better than oral gabapentin alone.
Keywords：Post-herpetic neuralgia2lidocaineGabapentin
Publication Date：2018-02-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 11-13 )