The study on the effect of seawater immersion and sunlight exposure on the skin of rats
Abstract：Objective To observe the changes of the skin of rats after seawater immersion and sunlight exposure, and to investigate the effect of seawater and sunlight on the skin. Methods The SD rats were immersed by seawater and exposed to simulated light (UVA +UVB), 5 times per week for 4 continuous weeks. The changes of skin appearance, moisture content and pathology were observed. Results The minimal erythema dose (MED) of the rats was 1443.6 mJ/cm2. Either seawater immersion or sunlight caused the decrease of moisture content of skin and dysfunction of the skin barrier, and the changes were more obvious after combined intervention. Histopathological findings revealed elastic fiber fracture, thickening and focal aggregation in the group of sequential seawater immersion or sunlight. The proliferation of keratinocytes was induced by seawater immersion or sunlight exposure, but the prognosis didn't become worse when the interventions were combined. Conclusion Exposure to sunlight after seawater immersion may exacerbate the photoaging and photodamage, which remind that the soldiers should strengthen the protection during sea training.
Keywords：PhotoagingSeawater immersionLightPhotodamage
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 193-196 )