Clinical curative effect observation of photodynamic therapy for moderate to severe acne
Abstract：ObjectiveTo observe the efifcacy and adverse reactions of 5-aminolevulinic acid photodynamic therapy in the treatment of moderate to severe acne. MethodsForty-one patients with moderate to severe facial acne were treated once every 10-15 days for three times continuously by 10% 5-aminolevulinic acid photodynamic therapy and followed up every two weeks for six weeks after the last treatment. The evaluation of efifcacy and the adverse effects were recorded at each follow-up. ResultsAfter 3 times of photodynamic therapy, the total effective rate of the 41 cases was 73.17%. With the increase of the treatment times, clinical efifcacy was gradually obvious. The effective rate of moderate and severe acne patients was 80% and 70.97% respectively. The data demonstrated that the effect of photodynamic therapy had no signiifcant differences between the moderate and severe acne patients. Two, four and six weeks after treatment, the effective rate turned to be 80.49%, 90.24% and 95.12%, which implied that the lesions may continue to get better and fade with the prolonging of time.ConclusionPhotodynamic therapy is a simple, effective and safe treatment method for moderate to severe acne, which is worthy of clinical promotion.
Keywords：Acnemoderate to severeAminolevulinic acidPhotodynamic therapy
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 306-309 )