Clinical observation of Huoxue Jiedu decoction for psoriasis vulgaris of Blood stasis syndrome
Abstract：ObjectiveTo evaluate the clinical effect and safety of activating blood and removing toxin decoction (huoxue jiedu decoction, HXJDD for short) in the treatment of psoriasis vulgaris of Blood stasis syndrome.MethodsThe randomized and controlled study was applied to 80 cases with psoriasis vulgaris. The treatment group was treated with HXJDD and control group was treated with placebo. The treatment lasted for 8 weeks and the efifcacy and safety were assessed. Main evaluation index included psoriasis area and severity index(PASI) score, main clinical symptoms of TCM, dermatology life quality index (DLQI) and safety indicators. ResultsThe total effective rate of HXJDD group was 86.84%, better than the control group 50.00%, and the difference was statistically signiifcant (P<0.05). Compared with control group after treatment, PASI score and DLQI score of the experimental group signiifcantly reduced, and the difference was statistically signiifcant (P<0.05). Signiifcant differences were found between the two groups of erythema and inifltration. Moreover, no serious adverse reactions occurred in the both groups.ConclusionHuoxue Jiedu decoction is safe and effective for psoriasis vulgaris of Blood stasis syndrome.
Keywords：PsoriasisvulgarisWhite mangeHuoxue Jiedu decoction(HXJDD)Blood stasis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 133-135,138 )