Research progress in the treatment of dystrophic epidermolysis bullosa
ZHUANG Bin-yu
LI Yu-zhen
Abstract：Dystrophic epidermolysis bullosa is a rare genetic disease, which is also a kind of mechanical bullous disease caused by the human body type VII collagen gene mutation or loss, characterized by skin blisters and scar formation, chronic and dififcult to heal wounds. According to the genetic type, the disease can be divided into dominant dystrophic epidermolysis bullosa and recessive dystrophic epidermolysis bullosa. In recent years, with the development of the study of DEB genetic and molecular pathogenesis, structure and function of type VII collagen, DEB treatment has gained a lot of new research results, some of which have carried out preclinical tests and clinical trials. In this paper, present treatment methods and new progress of DEB are summarized.
Keywords：Epidermolysis bullosadystrophicCollagen type ⅦTreatment
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 127-129,132 )