Analysis of 15 cases with pyoderma gangrenosum
DING Yuan
LU Qing-li
KANG Xiao-jing
Abstract：Objective To cognize pyoderma gangrenosum’s(PG) characteristic clinical aspects, pathological characteristics and treatment methods. Methods A retrospective study were performed based on15 cases of PG during a 5-year period. Results A total of 15 patients were included, 6 women and 9 men, with a 1.5:1 F:M ratio. Ten cases (66.67%) were ulcerative variant. The underlying diseases were rheumatoid arthritis, ulcerative colitis, chronic hepatitis B, pneumonia, and severe anemia. Vasculitis was seen in the border of ulcer and satellite lesions without ulcer. Conclusion The ulcerative variant was the most frequent form of PG in our study, Pathological changes depend on the site from which a biopsy specimen is obtained in a given lesion. The therapy of thalidomide combined with cyclophosphamide is effective, which with lower recurrence rate.
Keywords：Pyoderma gangrenosumAnalysisclinical
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 15-17 )