Lupus erythematosus tumidus：19 cases report and literature review
SHI Dong-mei
YAN Hong-xia
JIA Hong
Abstract：ObjectiveTo explore the clinical and pathologic character, treatment strategy and prognoses of lupus erythematosus tumidus (LET).MethodSix cases of LET diagnosed by the author, from 2009 to 2014, as well as other 13 cases reported in China were collected, and the clinical and pathological data were analysed (the other 4 patients unable to track the details were excluded in this retrospective analysis).ResultsThere were 9 males and 10 females among the 19 patients with TC who were aged from 19 to 58 years (mean age: 38.1 years). Clinically, the skin lesions mainly presented on the sun-exposed areas, minority of the skin lesions were distributed on the un-sun-exposed areas. There were 2 cases complicated with alopecia. Histopathology features include: lymphocytic, perivascular and periadnexal inifltrate with abundant interstitial, superifcial, and deep dermal mucin deposition without appreciable epidermal and vacuolar changes. Typically, LET is responsive to the treatment of systemic antimalarials. ConclusionLET is a special form of chronic cutaneous lupus erythematosus. The clinical manifestation of LET is relatively special and has no uniifed diagnostic criteria. The lack of understanding of the disease led to the misdiagnosis and deferment of the symptoms in patients. It is necessary to improve the understanding of LET, so as to give the correct diagnosis and effective treatment.
Keywords：Lupus erythematosus tumidusHydroxychloquine sulphate
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 332-335 )