Retrospective study on the management of skin lesions in 22 patients with toxic epidermal necrolysis
Abstract：Objective To retrospectively analyze the effects of management techniques including systemic and topical therapeutic treatments for patients with toxic epidermal necrolysis(TEN). Methods The comprehensive therapy based on systemic treatments such as anti-shock, anti-infection, anti-allergic drug and primary disease treatment. Topical treatments for skin lesions included applications of acellular dermal sheet, nano silver dressing, artiifcial cellular healing membrane, growth factor, suspension bed, wound therapeutic apparatus and semi-conductive laser. Results Among these 22 patients, 19 patients were cured and discharged, 1 patient died from pulmonary embolism and 2 patients died from septic shock. Conclusions Systemic measures play key roles in maintaining stability of internal environment, which may control the progression of skin lesions and decrease the incidence of infection. Topical measures also play key roles in TEN treatment, e.g. relieving wound deepening by application of suspension bed, decreasing the incidence of wound infection by nano silver dressing, accelerating wound healing and reducing the pain of patients by application of acellular dermal sheet, artiifcial cellular healing membrane, growth factor and semi-conductive laser, etc.
Keywords：Toxic epidermal necrolysisEpidermolysis bullosa eruptionNano sliver dressingPorcine acellular dermal dressingActived carbon ifber dressing
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 274-276 )