The clinical research of three treatment methods of 5-aminolevulinic acid photodynamic therapy for moderate to severe acne
SHEN Xiao-jiao
QIN Xiao-lei
YU Bo
Abstract：Objective To observe the efficacy and safety of three different methods of 5-aminolevulinic acid photodynamic therapy(ALA-PDT) to treat moderate to severe acne. Methods Sixty patients with moderate to severe acne were randomly divided into three groups and treated with different strategies. Group A were treated with one basic course. Group B were treated with one basic course and one maintaining course. Group C were treated with two basic courses. The effect and adverse reaction were evaluated on 1, 3, 6 and 12-month visit after the last treatment. Results The effective rates of three groups were 80%, 90% and 88.2%respectively on 3-month visit, and were 55%, 85%, 88.2%respectively on 6-month visit. The recurrence rates were 60%, 20% and 52.9% respectively on 12-month visit. Conclusion ALA-PDT is safe and effective for moderate to severe acne. Two basic courses or one basic course with one maintaining course were both effect but one basic course with one maintaining course has lowest recurrence rate.
Keywords：Acnemoderate to severe5-aomapeviomoc acid photodynamic therapyRecurrence rate
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 249-252 )