Comparison between 308 nm monochromatic excimer light and narrowband ultraviolet B phototherapy in the treatment of facial vitiligo
CONG Lin
WU Ying-ying
YANG Rong-ya
Abstract：Objective To compare the efifcacy of 308nm monochromatic excimer light (MEL) and narrowband ultraviolet B (NB-UVB) phototherapy in the treatment of facial vitiligo. Methods One lesion in facial vitiligo patient was treated with the 308nm MEL and its jacent or symmetrical lesion was treated with the NB-UVB. Lesions were treated two times a week for a total of 20 sessions. Results 308 nm MEL group obtained score 2 repigmentation required a mean of (8.6±1.31) treatments, while NB-UVB group required more treatments (15.8±4.29) to achieve the same result (P<0.05). The total effective rate of 308 nm MEL group and NB-UVB group was 92.13%and 86.52%respectively, with no signiifcant difference (P>0.05). Of these lesions, 42.70%treated with 308 nm MEL and 31.46%treated with NB-UVB achieved an excellent repigmentation, there was signiifcant difference between the two group ( P<0.05). The adverse reaction was transient erythema and blister, and all patients of the two groups were well tolerant. Conclusion 308 nm MEL is more effective than NB-UVB in treating facial vitiligo and it induces repigmentation more rapidly, the adverse reaction is similar.
Keywords：Vitiligoface308 nm excimer lightUltraviolet Bnarrowband
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 178-180 )