Analysis of interleukin level in serofast syphilis patients
Abstract：ObjectiveTo investigate the clinical significance of interleukin level detection of serofast syphilis patients. MethodsThirty-ifve serofast syphilis patients admitted to the seventh people’s hospital of Shenzhen city from January, 2009 to January, 2013 (observation group), 40 syphilis patients with negative RPR after treatment (control group 1) and 40 healthy subjects (control group 2) were enrolled in the study, all the patients underwent serum interleukin (IL) detection of IL-2, IL-12, IL-4, IL-10 levels and NK cell content determination.ResultsThe serum IL-2, IL-12 levels of the observation group were lower than those of the two control groups (P=0.000); the serum IL-4 and IL-10 levels of the observation group were higher than those of the two control groups (P=0.000~0.040), and the control group 1 was higher than that of the control group 2 (P=0.043,0.031); NK cell percentage of the control group 2 was higher than that of the observation group (P=0.000), the differences mentioned above all had statistical signiifcance.ConclusionSerofast syphilis patients may have cellular immune function suppression, which may be one of the causes of serofast formation.
Keywords：SyphilisSerofastInterleukins
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 102-103,106 )