Therapeutic effect observation of low-dose hydroxychloroquine sulfate for facial hormone-dependent dermatitis
LIU Zhen-feng
REN Hui-bin
Abstract：ObjectiveTo evaluate the efifcacy and safety of low-dose hydroxychloroquine sulfate in the treatment of facial hormone-dependent dermatitis.MethodsForty-eight patients with facial hormone-dependent dermatitis were randomly divided into two groups. The control group received epinastine hydrochloride tablets, once a day, and topical zinc oxide ointment, twice a day. In addition to the basic treatment of the control group, the treatment group received low-dose hydroxychloroquine sulfate orally. The duration of treatment lasted for 4 weeks.ResultsThe efifciency of the treatment group (83.3%) was signiifcantly higher than that of the control group(58.3%). The scores of the treatment group were signiifcantly lower than that of the control group at each observation point set in every week of the treatment (P<0.05).ConclusionIt is maybe more effective to treat facial hormone-dependent dermatitis with low-dose hydroxychloroquine sulfate, which with less side effects.
Keywords：Dermatitishormone-dependentHydroxychloroquineTherapeutic effect
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 423-424 )