Multi-center clinical observation of medical hydrogel as cooling dressings application to laser dermatology

doi:10.11786/sypfbxzz.1674-1293.20140311

Abstract：ObjectiveTo evaluate the safety, efficacy, and patient acceptance of hydrogel dressings applied in laser dermatology. MethodsOne hundred patients underwent laser dermatology were selected randomly over 6 hospitals in China. The hydrogel dressing was applied to their corresponding treatment skin as cooling material, which laser directly went through. Intense pulsed light therapy in 52 cases, laser hair removal in 26 cases and 22 cases of pigmented diseases were selected. Using self control, half face (side limb) using hydrogel, the other half as blank control. In a hydrogel coated on the laser treatment in site would before treatment, laser hair removal, directly through the hydrogel treatment laser, intense pulsed light in the treatment of water gel instead of conventional gel, other laser surgery would be pasted on the laser treatment in site hydrogel. Respectively during the operation, after 30 minutes and 7 days after operation to observe and evaluate the patient and physician assessment of the incidence of clinical symptoms and signs, doctor VAS score and adverse reactions.ResultsThere were signiifcant difference in the operative& postoperative criteria of bruises, pain, erythema and swelling between the side of the hydrogel and the control side (P<0.05). The score of clinical symptoms after 30 minutes in hydrogel side was better than the control side after treatment (P<0.05). There were no signiifcant difference after 7 days between two sides (P>0.05). And there were no complications of surface irregularities or contact dermatitis from the application or maintenance of hydrogel dressings.ConclusionsHydrogel dressings are safe and effective to reduce side effects of laser dermatology and patients are compliant with overall acceptance.