The unspeciifc T cell immunohistochemical markers in the diagnosis of mycosis fungoides granulomaclinical research progress
LI Hui
PU Xiong-ming
Abstract：Mycosis fungoides (MF) is a very common cutaneous lymphoma, because of its lack of characteristic clinical and pathological change, so for the diagnosis of the disease is often necessary to use a variety of auxiliary means, such as immunohistochemical, gene rearrangement, flow cytometry instrument and FISH.The immunohistochemical technique is one of the most common and widely used technique, what’s more, it is helpful for the early diagnosis of MF. However, expression of immunohistochemical markers at different stage of mycosis fungoides are variety. Consulting the relevant literatures, this paper probes further into immunohistochemical markers such as COX-2, Ki-67, PDCD1, p53, cell adhesion molecule, interleukin, chemokines, chemokines of receptors and survivin, reviewing the expression of immunohistochemical markers in the skin lesions of patients with MF in different stages, in order to provide necessary help for the early diagnosis of MF.
Keywords：Mycosis fungoidesImmunohistochemistryDiagnosis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 28-30,33 )