Efifcacy of 308 nm excimer light combined with tacrolimus ointment 0.03%in the treatment of facial vitiligo
Abstract：Objective To evaluate the efifcacy and safety of 308 nm excimer light combined with tacrolimus ointment 0.03%for facial vitiligo. Methods A total of 129 outpatients with facial vitiligo were randomly divided into three groups, each group included 43 cases. Group A as the treatment group, treated with 308 nm excimer light combined with tacrolimus ointment 0.03%;Group B and C as controls were respectively treated with 308 nm excimer light or tacrolimus ointment 0.03%. The study lasted for 12 weeks or finished until complete repigmentation of the lesions. Results The signiifcant efifciency of the group A, B and C was 73.80%, 47.61%and 17.07%respectively, there was signiifcant difference between the group A and the other two groups (P<0.05). There was no serious adverse reaction occurred in all the patients. Conclusion For the treatment of facial vitiligo, the efifciency of 308 nm excimer light combined with tacrolimus ointment 0.03%is signiifcant higher than the monotherapy, meanwhile with fewer adverse reactions.
Keywords：Vitiligoface308-nm excimer lightTacrolimus
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 343-345 )