Research progress on facial absorbable injection materials
GUO Jinhai
YUAN Yuting
ZHOU Xinrong
Abstract：Absorbable injectable materials for facial rejuvenation have gained significant traction in minimally invasive aesthetic medicine owing to their favorable biocompatibility,degradability,and low immunogenic risk.Representative materials include:hyaluronic acid(HA),collagen(CLG),poly-L-lactic acid(PLLA),polycaprolactone(PCL),and calcium hydroxylapatite(CaHA).They have demon-strated not only substantial efficacy in volumizing and contour restoration,but also in promoting collagen neogenesis,improving skin tex-ture,and delaying facial aging.This review systematically summarizes the physicochemical characteristics and biological mechanisms of the five principal absorbable injectable materials,along with their formulation forms,clinical techniques,and multi-site indications.The emerging trends of combination therapy and structural optimization are also discussed.
Keywords：Hyaluronic acidCollagenPoly-L-lactic acidPolycaprolactoneCalcium hydroxylapatiteAbsorbable injectable materials
Publication Date：2026-02-15
Online Publishing Date：2026-03-31(First online date of this platform, not the publication date of the document)
Pages：6( 79-84 )