Clinical application of combined macrofat and microfat layered grafting for the correction of temporal depression
XU Jiaxue
ZHENG Liang
YANG Fan
XU Fengrui
LIU Wei
Abstract：Objective To investigate the safety and clinical efficacy of combined macrofat and microfat layered grafting in the correction of temporal depression.Methods A retrospective analysis was conducted on 38 patients from June 2019 to June 2024.Adipose tissue was harvested from the medial thigh using vacuum-assisted liposuction.Macrofat(centrifuged at 1200×g)and microfat(prepared via mechanical emulsification followed by 200×gcentrifugation)were prepared respectively.During the procedure,macrofat was injected into the deep temporal space to provide structural support,while microfat was injected into the subcutaneous fat layer for refined contouring.The injection volume per side ranged from 8 to 15 mL until the temporal area reached a state of noticeable over-correction.Patient satisfaction and complications were evaluated during the follow-up period.Results Patient satisfaction rates at 1,3,and 6 months postoperatively were 89.47%,78.94%,and 68.42%,respectively.The difference in efficacy between preoperative and 6 month postoperative assess-ments was statistically significant(P<0.05).Significant improvement in temporal depression was observed in all cases.Five patients achieved satisfactory results after a second filling procedure.No palpable nodules,secondary deformities,or paresthesia were reported.Conclusion Combined macrofat and microfat layered grafting is a safe and effective approach for correcting temporal depression.It yields satisfactory clinical outcomes and merits wider clinical promotion.
Keywords：Temporal depressionGranular fatFat transplantation
Publication Date：2026-02-15
Online Publishing Date：2026-03-31(First online date of this platform, not the publication date of the document)
Pages：4( 76-78,84 )