The impacts of oral levovitamin C combined with Q-switched laser on the degree of pigmentation and skin elasticity in pa-tients with facial traumatic pigmentation
LIU Yingqi
REN Zhixin
LIU Shuo
TIAN Yan
Abstract：Objective To investigate the impacts of oral levovitamin C combined with Q-switched laser on the degree of pigmen-tation and skin elasticity in patients with facial traumatic pigmentation.Methods A total of 186 patients diagnosed with pigmentation in Hebei University of Engineering Affiliated Hospital From September 2021 to March 2024 were collected and stochastically separated into a laser group and a combined treatment group by random number table method,with 93 patients in each group.The laser group used Q-switched laser,while the combined treatment group used a combination of levonorepinephrine and Q-switched laser.The clinical effi-cacy,skin indicators,pigmentation symptom scores,oxidative indicators,hormone levels[follicle stimulating hormone(FSH),estradiol(E2)],melanin index(MI),erythema index(EI),and untoward reactions were compared between the two groups after treatment.Results After treatment,the total effective rate of the combined treatment group was 94.62％,which was prominently higher than the 83.87％of the laser group(P＜0.05).The scores of pigmentation symptoms,MI,EI,lipid peroxidation(LPO),FSH,and E2 levels in both groups were promi-nently reduced compared to before treatment(P＜0.05),and the combined treatment group was lower than the laser group(P＜0.05).The stratum corneum moisture content,skin elasticity,and superoxide dismutase(SOD)level in both groups were prominently increased com-pared to before treatment,and the combined treatment group was higher than the laser group(P＜0.05).There was no prominent difference in the incidence of untoward reactions between the combined treatment group and the laser group(P＞0.05).Conclusion The combination of levovitamin C and Q-switched laser therapy can improve clinical efficacy,alleviate pigmentation symptoms,reduce degrees of pigmenta-tion and oxidation,improve skin elasticity,and have high safety in patients with facial traumatic pigmentation.
Keywords：Post-traumatic pigmentationLevovitamin CQ-switched laserDegree of pigmentationSkin elasticity
Publication Date：2025-10-15
Online Publishing Date：2025-11-25(First online date of this platform, not the publication date of the document)
Pages：4( 610-613 )