Application effect of CO2 frational laser combined with comprehensive rehabilitation measures on patients with hand burn scar contracture

CUI Chengming; SHI Wanqiu

doi:10.3969/j.issn.1673-7040.2025.10.005

Abstract：Objective To observe the application effect of CO2 frational laser combined with comprehensive rehabilitation mea-sures on patients with hand burns,scars,and contractures.Methods A prospective randomized controlled trial was conducted on 118 patients with hand burns,scars,and contractures admitted to our hospital from January 2023 to June 2024.The patients were divided into two groups using the drawing method.59 patients with odd numbers were selected as the control group,and 59 patients with even numbers were selected as the laser group.The control group received conventional comprehensive rehabilitation treatment,while the laser group re-ceived CO2 frational laser combined with conventional rehabilitation treatment.After treatment,the patients were followed up for one year to compare the scar improvement,wound growth,incidence of complications,and hand function recovery between the two groups.Results Under different treatment plans,the scar color,thickness,vascular distribution,and softness scores on the VSS in the laser group were lower than those in the conventional group(t=8.680,8.097,12.009,6.357;P＜0.05).The levels of EGF,PDGF,TGF-β1,and bFGF in the laser group were higher than those in the conventional group(t=3.533,3.820,3.504,4.593;P＜0.05).During the follow-up period,the incidence of complications in the laser group was 6.78％(4/59)lower than that in the conventional group,which was 20.34％(12/59)(x2=4.628;P＜0.05).As of the end of follow-up,the MCP,PIP,DIP,and hand grip strength of the laser group were(60.35±10.41)°,(70.24±10.39)°,(40.25±5.37)°,and(20.35±3.55)kg,respectively,all higher than those of the conventional group[(55.42±10.36)°,(65.39±10.45)°,(37.52±5.46)°,and(18.65±3.47)kg](t=2.578,2.528,2.738,2.630;P＜0.05).Conclusion CO2 frational laser combined with comprehensive rehabilitation therapy can improve the scar condition of patients with hand burn scar contracture,promote wound growth,reduce the risk of complications,and promote hand function recovery,all of which have positive significance.