Progress in biotherapy for androgenetic alopecia
LIN Xin
ZHOU Ling
SHEN Yanbing
TANG Fangqi
QIU Weiming
XU Kai
Abstract：Androgenetic alopecia(AGA)is a common type of alopecia globally.To identify relevant studies on biological therapies for AGA,a comprehensive search was conducted across multiple databases,including the Cochrane Library,Medline,PubMed,Wanfang,CNKI,EMBASE,and Scopus.Keywords such as"stem cells""hair regeneration""androgen-dependent alopecia""platelet-rich plasma""cell therapy"and"exosomes"were utilized to retrieve pertinent research.The review revealed that various cell-based therapies,such as mesenchymal stem cells,adipose-derived stem cells,extracellular matrix,and even hair follicle stem cells,can significantly enhance hair density and diameter in AGA patients.Similarly,non-cell-based approaches,including platelet-rich plasma,vesicles,exosomes,and stem cell-conditioned medium,have also demonstrated the ability to significantly improve hair density and diameter.These findings suggest that biological therapies hold considerable promise for the treatment of androgenetic alopecia.
Keywords：Androgenetic alopeciaRegenerative therapyPlatelet-rich plasmaExosomes stem cellsStem cell derivatives
Publication Date：2025-05-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 305-310 )