The mechanism and research prospects of white hair formation
LIU Yuhang
XIAO Zhibo
Abstract：Hair graying is one of the most intuitive phenotypes of human aging.Although the specific role of genetic factors in gray hair is still uncertain,studies have found that oxidative stress,emotional stress,neuroendocrine regulation,diseases,and trace elements contained in the body may all be related to the generation of white hair.Melanin production in hair follicles is strictly coupled to the nascent stage of the hair growth cycle.Melanin stem cell self-maintenance defects and melanocyte synthesis disorders under the regulation of vari-ous hormones and biological factors in the process of pigment synthesis may be the key to the generation of white hair.This article reviews the recent research on the mechanism of white hair formation and the future prospects for the prevention and treatment of white hair from different aspects.
Keywords：Hair grayingHair follicleMelanocyteMelanocyte stem cells
Publication Date：2025-01-14
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 64,后插1-后插4 )