Clinical study on cosmetic effect of botulinum toxin A on nasal tip
SHAO Deliang
SHI Jie
GAO Jingnan
HAN Mingqian
GU Dongjiang
LIU Xiaoguang
YUAN Jilong
Abstract：Objective To observe the cosmetic effects and adverse reactions of single and multi-point botulinum toxin A injection in the nasal tip region.Methods From June 2022 to April 2023,47 subjects were injected with botulinum toxin A.The experimental data were collected before injection,4 weeks after injection,and 12 weeks after injection.Repeated measures analysis of variance and non-parametric test were used for data analysis,and IPA method was used for satisfaction analysis.Results All subjects experienced no adverse reactions or complications.The nasal tip protrusion increased after injection,with a statistically significant change(P＜0.001);the nasal tip width decreased,with a statistically significant change(P＜0.001);the rating of pores on the nasal tip improved,with a statistically significant change(P＜0.001);the amount of sebum secretion on the nasal tip decreased,with a statistically significant change(P＜0.05).The IPA satis-faction analysis results showed that the subjects'expectations and satisfaction with improvements in nasal tip protrusion,and width were lower than average,while their expectations and satisfaction with improvements in pores and sebum secretion were higher than average.Conclusion Botulinum toxin A injection into the nasal tip is safe with a low incidence of adverse reactions and complications.Its effect on improving skin conditions such as reducing pores and sebum secretion is significant,with high satisfaction;its effect on increasing nasal tip protrusion and reducing nasal tip width,although statistically significant,has lower satisfaction.
Keywords：Botulinum toxin ANasal tip cosmetologyClinical study
Publication Date：2025-01-14
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 35-37,后插6 )