Clinical pathological analysis of 9 patients with subcutaneous panniculitis-like T-cell lymphoma
HOU Hui
LIANG Ying-hong
YUAN Ji-long
JING Shi-bing
Abstract：Objective To explore the pathomorphological features,histogenesis,diagnosis,differential diagnosis,treatment,and prognosis of subcutaneous panniculitis-like T-cell lymphoma (SPTCL).Methods From 2015 to 2017 Specimens of 9 patients with SPTCL were stained by the HE and immunohistochemical SP methods.The related literature was reviewed.Results All patients showed subcutaneous nodules and/or hard nodular erythema at different sites,with or without lymphadenectasis.All patients had typical histopathological and immunophenotypic changes and tumor cells infiltrating subcutaneous adipose tissue.The lymphoma cells were arranged around a single adipocyte,medium or large cells,and chromatin stained thicker under the microscope.The immunohistochemical T-cell markers were positive,and the B cell markers were not expressed.Conclusion SPTCL is a rare cutaneous T-cell lymphoma.Its clinical manifestations are lack of specificity and poor prognosis.However,it has relatively characteristic histopathological features and immunohistochemical phenotypes.A pathological examination can provide assistance for clinicians to formulate treatment strategies.
Keywords：Subcutaneous panniculitis-like T-cell lymphomaClinical pathologyLmmunohistochemistry
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 171-173 )