A preliminary study on three-dimensional visualization of human skin microstructure
CHEN Wei
CHEN Jia-jun
MA Jian-hua
LIN Li
XIN Yu
CHAI Gang
ZHANG Yan
WANG Shen
Abstract：Objective To establish a digitalized 3D visualization method of human skin microstructure based on computer graphics. Methods The scalp and subcutaneous tissues of 1 female patient who underwent rhytidectomy were subjected to continuous paraffin section with HE staining. One hundred digital images (1280×960 pixels) of 4μm slice thickness were photographed under a 20 times microscope. The continuous 2D images were aligned manually using Photoshop CS6 software to eliminate image distortion. The 3D microstructure of the skin was reconstructed by ImageJ software. Results Using ImageJ software, the motion 3D display of skin mi-crostructure can be displayed, andmulti-angular 2D images can be reconstructed. Motion and media files (.avi and .gif) were created, which can be opened invarioussoftware. Conclusion This research established a method of skin microstructure 3D visualization. By successfully modeling the space distribution of skin cells, it is possible to realizea skin cell 3D bio-print in the future.
Keywords：3D digital reconstructionSkin microstructureImageJ3D cell biological printing
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 5-7,11 )