Influencing factors of hyperuricemia among residents in a certain region

Zhang Jing

doi:10.3969/j.issn.1674-7151.2025.04.011

Abstract：Objective To explore the prevalence and influencing factors of gout among residents in Chifeng area,Inner Mongolia Autonomous Region.Methods The laboratory data of 1 126 examinees in the Physical Examination Center of Chifeng Songshan Hospital from January to June 2025 were collected,including gender,age,serum uric acid(UA),total cholesterol(TC),triacylglycerol(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C)and blood glucose(GLU).According to whether they had gout or not,they were divided into gout group(124 cases)and control group(1 102 cases),and the differences of above indicators between two groups were compared.There were 78 males and 46 females in gout group,and they were divided into 20-40 years old group(47 cases),41-60 years old group(70 cases)and≥61 years old group(7 cases)according to age.The differences in above indicators between gout group and control group,as well as the level of UA among gout patients of different genders and age groups were analyzed.Results The proportion of males among gout patients was significantly higher than that of females(62.90%vs.37.10%,P<0.05).The proportion of gout patients in 41-60 years old group had the highest proportion(56.45%),and those in≥61 years old group had the lowest proportion(2.98%).Among male gout patients,the level of UA in 41-60 years old group was significantly higher than those in 20-40 years old group and≥61 years old group(mmol/L:532.76±79.54 vs.489.38±71.32,471.51±42.29,both P<0.05).Among female gout patients,the level of UA in 41-60 years old group was higher than that in 20-40 years old group(mmol/L:424.47±58.71 vs.406.33±41.00,409.93±34.75,all P<0.05).The levels of TG and GLU in gout patients were higher than those in control group,and the level of HDL-C was lower than that of control group[TG(mmol/L):2.43±0.53 vs.1.57±0.58;GLU(mmol/L):6.04±1.25 vs.5.07±0.52;HDL-C(mmol/L):1.09±0.16 vs.1.51±0.32;all P<0.05).Conclusions The proportion of male gout patients in Chifeng area is higher than that of female patients.The UA level of gout patients in 41-60 years old group is the highest,and TG may be an important factor causing gout in the population of this area.