One case of anti-K antibody detected in a patient with multiple blood transfusions
Zhang Qi
Chen Ye
Wang Lili
Abstract：Objective To report a patient who received multiple blood transfusions,and irregular antibodies were found in immunoserological testing and identified as anti-K antibodies with immunoglobulin G(IgG)properties.Methods On October 1,2024,the Fifth Affiliated Hospital of Xinjiang Medical University admitted a female patient with chronic renal failure and need for blood transfusion,the routine ABO and RhD blood type identification and antibody screening were performed.The antibody identification of the patient was carried out by the saline tube method(NS)and microcolumn gel method(MGT).The nature of antibody was clarified and the possible reasons for antibody production were analyzed.Results The patient was a 70-year-old female admitted to the hospital due to chronic renal failure,with a history of multiple blood transfusions in the hospital.After admission,the patient's blood type was found to be O Rh(D)positive,and the antibody screening test was positive.Antibody specificity identification detected the presence of IgG anti-K antibodies in the serum.Conclusions The patient developed anti-K irregular antibodies after multiple blood transfusion immunostimulation.It is necessary to conduct irregular antibody screening and specific identification for patients who have received multiple blood transfusions before blood transfusion.
Keywords：Irregular antibody screeningSpecificity identificationKell blood typeAnti-K antibody
Publication Date：2025-06-30
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 176-178 )