Distribution characteristics and risk factors analysis of patients with hyperuricemia

Guo Jinjie; Li Zhaolong; Yu Haixiao

doi:10.3969/j.issn.1674-7151.2025.01.013

Abstract：Objective To analyze hyperuricemia(HUA)detectable rate in Chifeng area of Inner Mongolia Autonomous Region,explore risk factors,and provide theoretical reference for the prevention of HUA in local population.Methods The clinical data[age,gender,serum uric acid(UA),triglyceride(TG),total cholesterol(TC),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C)and fasting blood glucose(FBG)]were collected from 3 519 patients in Chifeng Songshan Hospital from January 1 to December 1,2024.According to UA level,the patients were divided into HUA group(547 cases)and control group(2 972 cases).According to age,they were divided into groups of<18 years old(67 cases),18-35 years old(602 cases),36-55 years old(1 636 cases),56-80 years old(1 094 cases)and≥81 years old(120 cases).The HUA detectable rates in patients of different genders and ages were compared.The blood glucose and lipid levels of patients were compared between HUA group and control group.Pearson correlation analysis was used to examine the correlation between HUA and blood lipid and glucose indicators.Results The detectable rate of HUA in males was higher than that in females[27.58%(492/1 784)vs.3.17%(55/1 735)],and the detectable rate of HUA was highest in 18-35 years old group,at 30.40%(183/602).The levels of TG,TC and HDL-C in HUA group were higher than those in control group[TG(mmol/L):2.39±1.49 vs.1.38±0.63;TC(mmol/L):5.94±0.24 vs.2.67±0.43;HDL-C(mmol/L):1.47±1.17 vs.1.32±0.37;all P<0.05].Pearson correlation analysis showed that HUA was positively correlated with abnormal TG and TC levels(r values were 0.458 and 0.221,both P<0.001).Conclusions The detectable rate of HUA in males in Chifeng area is higher than that in females,and the age of onset is mainly 18-35 years old.HUA is associated with abnormal TG and TC levels.