Effect of combined detection of blood glucose and blood lipid indexes in diagnosis of diabetes mellitus

Wang Qihua; Lin Yunxia

doi:10.3969/j.issn.1674-7151.2024.03.014

Abstract：Objective To investigate the effect of biochemical tests in the diagnosis of diabetes mellitus.Methods The 60 patients with diabetes mellitus who visited Shanxian County Horticultural Community Health Service Center from September 2021 to September 2023 and 60 healthy examinees in the same period were selected as research objects,and were respectively included in diabetes mellitus group and healthy control group.The patients in both groups underwent biochemical tests,the levels of fasting blood glucose(FBG)and 2-hour postprandial blood glucose(2hPG)were detected using oxidase method,the level of glycosylated hemoglobin(HbA1c)was detected using HbA1c analyzer,and the levels of total cholesterol(TC),triacylglycerol(TG),low-density lipoprotein cholesterol(LDL-C)and high-density lipoprotein cholesterol(HDL-C)were measured using fully automated biochemical analyzer.The detectable rates of HbA1c and TG separately and in combination were compared.Results The levels of FBG,HbA1c,2hPG,TC,TG and LDL-C in diabetes mellitus group were significantly higher than those in healthy control group,while the level of HDL-C was significantly lower than that in healthy control group[FBG(mmol/L):9.18±2.01 vs.5.31±0.47;HbA1c:0.073±0.008 vs.0.051±0.004;2hPG(mmol/L):12.03±2.46 vs.6.10±0.62;TC(mmol/L):5.89±0.63 vs.3.69±0.50;TG(mmol/L):2.95±0.47 vs.1.20±0.22;LDL-C(mmol/L):3.68±0.84 vs.2.08±0.42;HDL-C(mmol/L):0.88±0.08 vs.1.45±0.16;all P＜0.05].The detectable rate of HbA1c and TG combined detection was significantly higher than those of HbA1c and TG detected alone[98.33%(59/60)vs.83.33%(50/60),63.33%(38/60),both P＜0.05].Conclusion Monitoring the changes of blood glucose and blood lipid indicators in biochemical tests is helpful for clinical diagnosis of diabetes mellitus,and joint detection of multiple indicators could improve the detectable rate of disease.