Application value of combined blood routine test indexes in classification of pediatric pneumonia

Du Siju

doi:10.3969/j.issn.1674-7151.2024.03.009

Abstract：Objective To analyze the application value of combined detection of blood routine test indexes in the classification of pediatric pneumonia.Methods The clinical data of 120 children with pediatric pneumonia admitted to pediatrics department of Yuqing County People's Hospital from January 2022 to December 2023 were collected.The children were divided into bacterial pneumonia group(50 cases),viral pneumonia group(30 cases)and mycoplasma pneumonia group(40 cases)according to the pathogen type.After collecting blood samples,the blood routine indicators[white blood cell count(WBC)and neutrophil proportion(NEU%)]were detected using fully automated blood cell analyzer.Using clinical diagnostic results as reference,the differential diagnostic efficacies of WBC and NEU%alone and in combination for bacterial pneumonia,viral pneumonia and mycoplasma pneumonia were analyzed,and the differences in sensitivity,specificity,positive predictive value and negative predictive value were compared.Results The levels of WBC and NEU%in bacterial pneumonia group were higher than those in viral pneumonia group and mycoplasma pneumonia group[WBC(×109/L):12.31±1.19 vs.6.52±1.02,8.93±1.10;NEU%:(67.23±7.34)%vs.(29.04±2.53)%,(53.11±5.10)%;all P＜0.05],and the levels of WBC and NEU%in mycoplasma pneumonia group were higher than those in viral pneumonia group(both P＜0.05).Based on clinical diagnosis,the sensitivity,specificity,positive predictive value and negative predictive value of combined detection of WBC and NEU%for differential diagnosis of pediatric pneumonia subtypes were higher than those of WBC and NEU%alone(bacterial pneumonia:sensitivity:83.33%vs.73.33%,66.67%,specificity:85.00%vs.70.00%,70.00%,positive predictive value:89.29%vs.78.57%,76.92%,negative predictive value:77.27%vs.63.64%,58.33%;viral pneumonia:sensitivity:70.00%vs.55.00%,50.00%,specificity:60.00%vs.40.00%,50.00%,positive predictive value:77.78%vs.64.71%,66.67%,negative predictive value:50.00%vs.30.77%,33.33%;mycoplasma pneumonia:sensitivity:54.17%vs.33.33%,37.50%,specificity:50.00%,37.50%,37.50%,positive predictive value:61.90%,44.44%,38.74%,negative predictive value:42.11%,27.27%,31.36%;all P＜0.05).Conclusions The changes in blood routine indicators are more significant in the classification of pediatric pneumonia,which could provide certain reference for distinguishing the types of pathogenic bacteria.Moreover,the diagnostic efficacy of combined detection is higher than those of individual testing,and it has good promotional value in primary medical institutions.