Distribution and sensitivity of bacteria in infected wounds of diabetes foot

Wu Shaojie; Wu Xuejun

doi:10.3969/j.issn.1674-7151.2023.04.018

Abstract：Objective To analyze the bacterial distribution and sensitivity in infected wound of diabetes foot.Methods From June 2021 to October 2022,84 patients with diabetes foot diagnosed in Fuzhou Second Hospital were selected as research objects.Results Gram negative(G-)bacteria,Gram positive(G+)bacteria,as well as Staphylococcus aureus and Pseudomonas aeruginosa accounted for relatively high proportions of 55.41%,42.52%,17.29%and 11.82%,respectively.The resistance rates of G+ bacteria to Penicillin and Erythromycin were the highest(59.66%and 51.40%).The sensitive rates to Vancomycin and Teicoplanin were the highest(100.00%and 99.03%).The sensitive rates of fungi to Itraconazole and Amphotericin B were both 100.00%,which were higher than Fluconazole(84.62%).The proportion of G-bacterial infection in patients with different Wagner grades was relatively high,with 21.95%for grades 1-2 and 78.05%for grades 3-5,and the next were G+ bacteria,with 33.87%for grades 1-2 and 65.35%for grades 3-5.Conclusions A variety of pathogenic bacteria could cause diabetes foot,and the drug resistance rate is generally high.Clinical treatment should choose reasonable intervention measures to maintain normal blood sugar levels in patients,conduct timely and multiple pathogen tests,in order to find the most suitable antibacterial drugs and promote patients to recover their health as soon as possible.