Application of pro-brain natriuretic peptide and procalcitonin levels detection in the ventilation offline
JIANG Cui-xia
Abstract：Objective To investigate the pro-brain natriuretic peptide (pro-BNP) and procalcitonin (PCT) levels detected in the application effect of mechanical ventilation in the offline analysis. Methods 80 patients in our hospital from January 2014 to December 2015 admitted with respiratory failure treated with me-chanical ventilation therapy were collected as research subjects. All subjects were given standard tests to achieve spontaneous breathing off machine , and which were divided into success group and failure group ac-cording offline research object. The levels of plasma pro-BNP, PCT, oxygenation index, average heart rate and mean arterial pressure and other indicators of all the patients were detected , and independent risk factors for the success of mechanical ventilation offline were analyzed. Results The levels of pro-BNP and PCT in success group were all lower than that of failure group , but oxygenation index was higher than that of failure group, and the differences all had statistical significance(Pall<0.05). The differences of average heart rate and mean arterial pressure of the two groups had no statistical significance (Pall>0.05). Pro-BNP and PCT were all independent risk factors for mechanical ventilation offline success. Conclusion The plasma pro-BNP and PCT levels can respond effectively offline risk mechanically ventilated patients , administration of a sponta-neous breathing trial linking and inspection of pro-BNP and PCT levels can be significantly improved mechan-ically ventilated patients offline success rate.
Keywords：Plasma brain natriuretic peptideProcalcitoninMechanical ventilationOfflineInde-pendent risk factors
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 103-105 )