Clinical application value of PCT in patients with sepsis in different pathological processes

doi:10.3969/j.issn.1674-7151.2016.02.009

Abstract：Objective To study the clinical application value of procalcitonin (PCT) in patients with sepsis in different pathological processes. Methods 120 patients with sepsis who were admitted in our hospi-tal between August 2010 and August 2015 were selected as study subjects. All the patients were divided into sepsis group (47 cases), severe sepsis group (39 cases) and septic shock group (34 cases) according to the pathogenetic condition. The concentrations of PCT were detected by immunofluorescence assay on the 1st to 7th day after admission. The results of PCT in different sepsis groups were analyzed statistically. Results The PCT levels showed a increasing trend along with the severity degree of sepsis. There were statistical significance in the differences of PCT levels among three different sepsis groups at different time(Pall<0.05). The PCT level in septic shock group was higher than that of severe sepsis group and sepsis group, and the severe sepsis group was higher than that of sepsis group, and the differences all had statistical significance (Pall<0.05). The PCT levels in three sepsis groups were all decreased along with the increase of hospitalization time. The PCT levels on 3rd, 5th and 7th day after admission in death group were all higher than that of survival group, and the dif-ferences all had statistical significance (Pall< 0.05). The PCT level in survival group showed a decreasing trend, but showed a increasing trend in death group along with the increasing hospitalization time, and the dif-ferences all had statistical significance(Pall<0.05). Conclusion The detection of PCT has better clinical ap-plication value in the diagnosis, therapy and prognosis evaluation.