The value of CEA and CA19-9 in rectal cancer diagnosis and therapeutic effect evaluation
ZHANG Jing
Abstract：Objective To research the value of carcino-embryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) in rectal cancer diagnosis and therapeutic effect evaluation. Methods 60 cases pa-tients with rectal cancer from May 2011 to May 2015 in our hospital were collected as observation group , and 70 cases healthy people at the same periods were collected as control group. The CEA and CA19-9 levels of all the subjects were detected by electrochemiluminescence method , and the results were analyzed statistically. Results The CEA and CA19-9 levels in observation group were all higher than that of control group , and the differences all had statistical significance (Pall<0.05). The sensitivity, specificity, and accuracy of CA19-9 were all higher than that of CEA in rectal cancer diagnosis. The sensitivity, specificity, and accuracy of CEA and CA19-9 combine detection were all higher than that of lonely detection. The CEA and CA19-9 levels were all showed a increasing trend along with the therapeutic effect worsen. There were statistical significance in the differences of CEA and CA19-9 levels among different effect groups (Pall<0.05), and the differences all had statistical significance between each two groups(Pall<0.05). Conclusion CEA and CA19-9 combine detec-tion can improve the detection rate of rectal cancer , and also have better clinical application value for thera-peutic effect evaluation.
Keywords：Rectal cancerCarcino-embryonic antigenCarbohydrate antigen 19-9Preoperative diagnosisEffect evaluation
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 91-93 )