Blood cell parameters of RPR and MPV value analysis for the forecast of hypertensive cerebral infarc-tion

ZHANG Jian-guo; LI Zhi-feng; TAO Ran

doi:10.3969/j.issn.1674-7151.2016.02.005

Abstract：Objective To study the predictive value of blood parameters of RDW platelet ratio (RPR) and mean platelet volume (MPV) in hypertensive cerebral infarction. Methods 262 cases patients with hy-pertensive cerebral infarction and 100 cases healthy people in our hospital from January 2014 to December 2015 were collected in the research. The platelet parameters and RDW data of all subjects were detected , and the RPR were calculated by RPR=RDW (%)/PLT (109/L). The diagnosis value of all data for hypertensive cerebral infarction were evaluated. Results The MPV, RDW and RPR levels in cerebral infarction group were all higher than that of healthy control group, but PLT level was lower than that of healthy control, and the dif-ferences all had statistical significance (Pall<0.05). There was no statistical significance in the difference of PDW level between the two groups (P>0.05). The area under receiver operating characteristic curve of RDW, MPV and RPR in diagnosis hypertensive cerebral infarction were 0.635, 0.640 and 0.676, respectively. When the cutoff value of RPR for hypertensive cerebral infarction diagnosis was 0.066, the sensitivity was 0.40, specificity was 0.86, positive predictive value was 0.86, negative predictive value was 0.36. When the cutoff value of MPV for hypertensive cerebral infarction diagnosis was 8.25 fl, the sensitivity was 0.81, specificity was 0.54, positive predictive value was 0.79, negative predictive value was 0.49. The correlation coefficient of RPR with MPV and PDW were 0.306 and 0.079 (Pall<0.01). Conclusion RPR and MPV have predictive value for hypertensive cerebral infarction , and the higher value of the parameters RPR.