Expression level and significance of 25-hydroxy vitamin D3 in serum of children with juvenile idiopath-ic arthritis
MA Zhi-chao
RUAN He-qiu
HUANG Bai-li
Abstract：Objective To study the expression and significance of 25-hydroxy vitamin D3 [25(OH) D3] in serum of children with juvenile idiopathic arthritis (JIA). Methods 78 cases of JIA children and 80 cases healthy children were collected from January 2014 to June 2015 in our hospital , and the concentration of 25 (OH)D3 in serum was detected by Roche diagnostic kit. The results were analyzed statistical ly. Results There were statistical significance in the difference of 25 (OH)D3 level among different types of JIA groups and control group(P<0.05). The 25(OH)D3 level of different types of JIA groups were all lower than that of control group, and the differences all had statistical significance(Pall<0.05). There were statistical significance in the differences of 25(OH)D3 level between each two types of JIA groups(Pall<0.05). The lack rate of generalized type JIA group (77.8%) was significantly higher than the other type groups , while the normal rate of oligoartic-ular JIA (62.5%) was higher than that of the systemic JIA group (11.1%) and the polyarticular JIA group (14.3%). Conclusion JIA children exist VitD deficiency, low levels of VitD and JIA have a certain correla-tion. Detection of VitD content may contribute to the diagnosis and treatment of JIA.
Keywords：25-hydroxy vitamin D3Juvenile idiopathic arthritisChildren
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 35-37 )