The clinical application of heart-fatty acid binding protein in AMI early diagnosis
Abstract：Objective To investigate the clinical application value of heart-fatty acid binding protein (H-FABP) in acute myocardial infarction(AMI) diagnosis. Methods 151 cases AMI patients in our hospital from January 2013 to June 2015 were collected as the AMI group. 68 cases patients with chest pain indications but obviated AMI during the same period were selected as the control group. The levels of H-FABP , cardiac troponin I(cTnI), creatine kinase(CK) and MB isoenzyme of creatine kinase(CK-MB) at 0-3 h, 3-6 h, 6-12 h of all the patients to fall in disease were detected. The results were analyzed statistically. Results The levels of H-FABP, cTnI, CK and CK-MB at 0-3 h, 3-6 h, 6-12 h in AMI group were all higher than that of control group, and the differences all had statistical significance (Pall<0.05). The sensitivity, specificity and area under receiver characteristic operating curve were 78.8%, 89.7%and 0.919, respectively, which were all higher than that of the other three index. There were better correlation among H-FABP and cTnI, CK, CK-MB during each period, and the coefficient correlation r were all higher than 0.8. Conclusion The diagnosis value of H-FABP is better than that of cTnI, CK and CK-MB in AMI diagnosis.
Keywords：Acute myocardial infarctionMyocardial damageHeart-fatty acid binding proteinCar-diac troponin ICreatine kinaseMB isoenzyme of creatine kinase
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 22-25 )