Drug resistance analysis and distribution characteristics of 396 strains of bacteria in genital tract infec-tion of women

doi:10.3969/j.issn.1674-7151.2015.03.011

Abstract：Objective To investigate distribution characteristics and drug resistance of bacteria in genital tract infection of women, and to provide the reference for clinical treatment. Methods 396 patients of pathogens from cervical secretion samples in gynecological inpatient and outpatient department were collected from January 2011 to June 2014. All samples were identified and their resistance to antibiotics were tested by DL 96 bacteria detection and analysis system. And the results of drug sensitive test were analyzed by WHONET 5.5. Results In 396 strains pathogens, gram-positive bacteria was 137 strains (34.60%), gram-negative bacteria was 102 strains (25.76%) and 157 strains (39.65%) were fungi, and the highest relevance ratio of bacteria were Enterococcus faecalis (37/396, 9.34%), Escherichia coli(50/396,12.63%) and Candida albi-cans(108/396, 27.27%), respectively. The results of drug sensitive test showed that the highest drug resis-tance rate of Enterococcus faecalis was erythromycin (91.89%), and the lowest drug resistance rate was te-icoplanin(0.00%). The highest drug resistance rate of Escherichia coli was ampicillin(80.00%), and the low-est drug resistance rate were imipenem (0.00%) and meropenem (0.00%). The highest drug resistance rate of Candida albicans was itraconazole(59.26%), and the lowest drug resistance rate was amphotericin B(1.85%). Conclusion There are many different kinds of pathogenic bacteria in genital tract infection of women , inves-tigating the distribution and drug resistance of the common bacteria is helpful for reasonable and safe applica-tion of antibacterial agents according to different clinical situations.