The change trend of Acinetobacter baumannii in our hospital from 2009 to 2013

LOU Jun; YANG Jia; QIU Wei-qiang

doi:10.3969/j.issn.1674-7151.2015.03.006

Abstract：Objective To understand the situation and drug resistant trend of Acinetobacter bauman-nii in our hospital from 2009 to 2013, and to provide laboratory basis for clinical rational use of antimicrobial agents. Methods 4373 strains Acinetobacter baumannii from inpatients were collected in our hospital from January 2009 to December 2013. The situation and drug resistant trend were analyzed in every year. Results The positive rates of Acinetobacter baumannii in our hospital from 2009 to 2013 were 790 strains(8.95%), 812 strains (9.02%), 872 strains (9.04%), 1025 strains (11.72%) and 874 strains (11.04%), respectively. The positive rates of Acinetobacter baumannii with extensive drug resistance were 364 strains (46.08%), 402 strains (49.51%), 446 strains (51.15%), 565 strains (55.12%) and 579 strains (66.25%), respectively. The highest positive rate of 4373 strains Acinetobacter baumannii was sputum specimens (87.50%). The mainly positive rates of Acinetobacter baumannii in clinical departments were respiratory intensive division(36.57%), ICU(31.95%) and respiratory medicine(7.55%). The higher drug resistance rates of 4373 strains Acinetobac-ter baumannii were penicillins, cephalosporins, quinolones, sulfanilamide and single circleβlactams, which were all more than 61.65%. And the drug resistance of Acinetobacter baumannii to carbapenems had rising trend obviously. Acinetobacter baumannii with extensive drug resistance to carbapenems had higher drug resis-tance rate, which were all more than 90.11%. And to polymyxin B had lowest drug resistance rate, which were all less than 1.73%. Conclusion Drug resistant situation of Acinetobacter baumannii is serious, and resistant rate increasing year by year. Doctor should rational use of antimicrobial agents , in order to reduce the occur-rence of extensively drug resistant.