Discuss the relationship between hyperuricemia and cranial vascular disease

WANG Qi; ZHANG Yan-chun

doi:10.3969/j.issn.1674-7151.2015.02.012

Abstract：Objective To discuss the relationship between hyperuricemia and cranial vascular dis-ease. Methods 143 cases hyperuricemia patients, which including 85 cases cerebral infarction patients (cerebral infarction group) and 58 cases cerebral hemorrhage patients (cerebral hemorrhage group) were se-lected in our hospital from August 2011 to June 2012. 156 cases healthy people(control group) were selected in the same time. Level of serum uric acid was detected by HITACHI-7600 automatic biochemical analyzer. All data were analyzed statistically. Results There was statistical significance in the difference of serum uric acid levels a-mong three groups(F=16.21, P<0.05). Levels of serum uric acid in cerebral infarction group and cerebral hem-orrhage group were all higher than that of control group, and the differences all had statistical significance (Pall<0.05). There was statistical significance in the difference of positive rate of hyperuricemia among three groups (χ2=4.572, P<0.05). The highest morbidity of hyperuricemia was cerebral infarction patients(41.18%). Con-clusion Abnormally elevated serum uric acid may indicate the occurrence of cranial vascular disease , but can not identify the disease type. Hyperuricemia can lead to the occurrence of cranial vascular disease. For pa-tients with cranial vascular disease should also pay attention to diagnosis and treatment of hyperuricemia dis-ease.